KPV 10MG

KPV (Kainic Acid-Potassium Valinate) is a synthetic peptide derived from kainic acid, a naturally occurring neuroexcitatory compound. This product is intended solely for academic, laboratory, or institutional research applications within a controlled research environment.

Research Context

KPV has been extensively studied in preclinical research for its potential effects on neuronal excitability, synaptic transmission, and neurotoxic mechanisms. Due to its ability to selectively stimulate certain neuronal populations while inducing neurotoxicity in others, KPV has been utilized in studies investigating neurodegenerative diseases, synaptic plasticity, and neuroprotection. It is commonly employed in animal models to investigate mechanisms of excitotoxicity, which plays a role in conditions such as stroke, epilepsy, and Alzheimer’s disease.

Research Overview

Kainic acid and its analogs, including KPV, are noncompetitive glutamate receptor agonists that bind to glutamate receptors, particularly the kainate receptor subtype. In preclinical research settings, KPV is often administered systemically or intracerebroventricularly in rodents to induce seizures or study neurotoxic pathways. Research involving KPV is typically conducted under strict laboratory protocols to ensure proper containment, safety measures, and ethical compliance with animal welfare standards.

Key Research Focus Areas

• Neurotoxicology: Investigation of KPV-induced neuronal damage and its implications in excitotoxicity-related diseases.
• Epileptogenesis: Examination of KPV’s role in inducing seizures and its potential for modeling epilepsy research.
• Synaptic Plasticity: Analysis of KPV’s effects on long-term potentiation (LTP) and long-term depression (LTD) in neuronal circuits.
• Neurodegeneration Models: Use in animal models to study mechanisms of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s.
• Neuroprotective Mechanisms: Exploration of potential neuroprotective strategies against KPV-induced damage.

Important Compliance Notice

This product is intended solely for academic, laboratory, or research purposes within a controlled, institutional environment. KPV is a potent neuroactive compound and poses significant risks when misused or administered outside a licensed research context. Users must adhere to strict regulatory guidelines, ethical standards, and safety protocols when handling and conducting research involving KPV.

For research use only. Not for human or animal consumption.